What is EROS?

Eros Male Enhancer is a Blend of 5 Powerful Ingredients Including Tongkat Ali, pumpkin, Mauria Puama, Maca in 60 Veggie Caps.

Eros is a high performance mixture and blend having 10 chief potent constituents including Vitamin A, Vitamin B1, Vitamin B3, Vitamin B5, Vitamin B6, Vitamin B12, Zinc, L arginine, L-Tyrosine, Bioperine and many other ingredients in proprietary blend including ginger, Tribulus Terrestris, Maca, ginseng root, extract of Tongkat Ali and ginger extract.

Eros male enhancement capsules are beneficial for any individual seeking support independent, high energy support, exercise performance, sex drive, increased stamina, and endurance.

Our product has the right and rational concentration of each constituent to deliver research-based, scientifically formulated and approved clean test booster that levels up your body energy by increasing metabolism endurance and vitality. You can trust our product, once you give chance you will feel its result.

Daily use of 2 Eros capsules twice a time daily brings a high energy level and libido in males. Take Eros consistently and routinely for 1 month (30 days) along with mild walk or a healthy exercise routine to get maximum benefits and results.

 

Reignite and trigger your fury, fire and increase your limits with the Eros advantage.

Our lab approved and verified unique blend and formula of 10 strong ingredients to support and help free t-levels, fight against the feelings and sensation of lethargy, loss of muscle mass, and improve and promote user stamina. Our product is 100% vegan with Non-GMO, constituents just like Tribulus Terrestris and ginkgo Biloba extract work in combination and blends to help and increase recovery time and get you back to your workout routine faster. Simply take as mentioned and directed on the label, be consistent, and pair with a healthy lifestyle for best results.

What you will get from Eros?


3-in-1 energy booster

Get the eros benefits! This one type of formula consists of powerful boosters developed after scientific research to support t-levels, fight against lethargy feelings and decline in muscle mass, and give you the stamina you’ve been looking for. Boost elite helps support free t-levels, sustained muscle mass, and improves stamina for a well-rounded formula you can trust.

Lean, clean & mean

All constituents are not created equal in nature. To deliver the best results, our clean herbal formula contains zero gluten, preservatives, or animal products. Here, the tribulus terrestris and fenugreek extracts in each vegetable capsule take centre stage to help restore vitality.

Level up energy

Boost energy level and this product are developed after research to increase your workouts, endurance, and energy levels. You don’t need to be a gymnastic or bodybuilder to see advantages! Eros is formulated to support and help a quick recovery time between workouts. In this way each workout can support you to burn your fat and gain body shape and muscle!

Light up your fire

You can get your strength and passion reverse. Eros is the most well-formulated research-based product in the market, having a strong and powerful blend of natural ingredients. You can trust us once and you’ll feel results of it in a short time. This is the time to trigger your passion. Eros provides you with the drive, you require to conquer each day at every place you roam and also at the gym.

Money back guarantee

We’re 100% confident that eros will enhance and help you to gain the results you have been set, we’ll return your hard-earned money if you’re not satisfied and thrilled with our product. You can simply contact us directly for a payment refund. No excuses, no tricks, we are providing the best guarantee in this global market.

Peak performance

Are you ready to enhance your game? Alleviate your energy levels, strength, and endurance along with supporting faster health recovery time with our product eros advantage!

Clean ingredients

Eros male enhancer provides a strong approach with five powerful natural ingredients along with zinc. There are no suspect ingredients in it, just clear and clean energy.

Powerful ingredients blend

Eros contains a potent natural blend of ingredients including zinc, tongkat ali, tribulus terrestris extract help test levels and support in building lean body muscle mass. Maca root extract supports reducing the body’s fat, improve exercise performance, enhance stamina and endurance. Panax ginseng helps improve physical stamina and concentration while decreasing stress. Extract of tongkat ali considered enhancing performance in males. The bark extract of yohimbe helps and support promotes energy and athletic performance.

EROS

is a Male Amplifier Having Natural Ingredients for Energy, Strength, Endurance and Performance!

  • NATURAL: All Pure Natural Ingredients
  • EFFECTIVE: Fast Acting & Long Lasting
  • GET REAL RESULTS
  • RISE AND SHINE
  • GUARANTEE: 100% SATISFACTION GUARANTEED OR YOUR MONEY BACK!!

PREMIUM NATURAL TESTOSTERONE BOOSTER

Eros is a well researched, scientifically-developed, blend of natural ingredients, having an all-natural supplement that is required to enhance natural testosterone level for men. Thus Eros is the world’s most effective research-based product having natural ingredients.

ENERGY, VITALITY, LIBIDO

Eros makes you feel a powerful sex desire, and an extreme drive to improve your workouts by increasing blood circulation. Eros improved your stamina and blood circulation thus help any person to perform better day by day both in as well as out of the bedroom.

STRENGTH, MUSCLE BUILDING, & FAT LOSS

Eros male enhancer helps in optimum muscle growth and development, burn fat content, and increase strength and endurance. You will be able to perform a better day by day and recover quickly from your gym workouts. Eros is the complete package to boost muscle growth and helps bodybuilders.

IMPROVED and ENHANCE MOOD

Eros improve your day with increased energy levels and alleviating vitality.

 

Zinc

Zinc is an essential mineral and present in the diet as a trace element. Chemically, zinc is an inorganic substance with a symbol of ‘Zn’. Enzymes also contain zinc and play an important role in protein synthesis and cell division. Zinc is also present in human blood and in the urine. Deficiency of zinc leads to several health problems including anaemia, growth retardation, geophagia, hypogonadism and delayed wound healing.

How does zinc supplement help to solve infertility?

Zinc acts as an aphrodisiac and can provide enhancement of libido. Zinc also has testosterone boosting property, especially in the case of zinc deficiency. Zinc is an essential element for the proper functioning of the immune system, endocrine system, an enzyme. It also inhibits the estrogen cycle and acts as an aromatase inhibitor. In addition, zinc supplementation can repair intestinal mucosa.

Zinc is an aphrodisiac and consumption of zinc supplement can enhance libido

Zinc boosts testosterone level and improves physical stamina, performance and delaying ejaculation and also improves sperm quality.

Zinc inhibits aromatase and reduces estrogen levels and effective to control sexual dysfunction.

Antioxidant effect of zinc can provide optimal health along with solving the prostate related problem.

Zinc can increase BDNF and improve mood and reduce depression.

Roles of Zn in the male reproductive system

 

Zinc in testis:

Zn present at high concentration in the vertebrates testes which can be compared to kidney and liver. In addition to that, there are special research reports that show that zinc can decrease testicular injury by stresses via various metals like fluorides, heat and heavy metals.

Zinc and male hormonal status:

Some researchers showed that Zn is essential for the functioning of the endocrine system in a normal way. Due to the chief role of zinc in male fertility and reproductive system, it is essential to remember that male variation is mostly related to zinc deficiency.

Zinc and prostate association:

The prostate gland as compared to other glands and tissues has more concentration of Zinc. The fact is that Zinc concentration is an indication of prostatic proper functioning. Its other major roles are maintenance and regulation of the metabolic functions of spermatozoa by acting as a co-factor for a number of enzymes, and also support in preservation of spermatic mobility and motility.

Antibacterial activity

Zn oxide nanoparticles have bactericidal effects on both gram-positive and gram-negative bacteria and are also effective against spores that are resistant to high temperature and high pressure (28.

Roles of Zn in the quality and function of sperm

Research evidence showed that seminal Zinc has a chief role in the metabolic and physiologic functioning of the spermatozoa such that it decreases the level result in minimum seminal quality and subsequent chances of fertilization.

Sperm quality

EROS has an optimum amount of zinc which along with other constituents present in the body like Cobalt and Selenium enhances and boosts the production of healthy, motile sperm having intact membranes.

 

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Tongkat Ali

History

It is recognized as a national treasure in Malaysia. This herb has an ancient history as a medicinal herb and has been in use for hundreds of years in continent Asia, especially in the regions of Malaysia, Thailand, and Indonesia.  It is also referred to as Ginseng of Malaysian region. This herb is a tiny evergreen tree present in the Malaysian jungles and Southeast Asia jungles.

Tongkat Ali Benefits

Male Sexual Health

Tongkat Ali is herb having powerful effects that have been used traditionally for hundreds of years for the disease-related to age, lethargy and physical endurance of males. Testosterone along with other hormones of the male are decreased in production as time passes leading to the condition called “andropause” commonly called “the male menopause” thus reduces the male efficiency in this regard. The most important symptoms associated with it are a considerable decrease in energy level, a decline in male libido, enhanced body fat and mental and nervous lethargy.

Many research studies indicated that Tongkat Ali root has compounds that trigger libido, stimulate and helps in proper sperm motility and quality of semen and helps in muscle growth. All the above-discussed effects discussed above are attributed to enhance testosterone levels. The support in the form of hormonal enhancement provided by our product EROS by providing Tongkat Ali also enhance male sperm quality thus promote fertility in male. This feature of our product is supported by a research study done in 2012 on 76 men having just 35% of whom had testosterone levels fall in normal range. By continuous supplementation of Tongkat Ali, after one month, the men having normal testosterone had risen prominently to 90%.

The most pleasant effect of this ingredient present in EROS is the significant alleviation in testosterone level thus a prominent sex drive boost takes place.

Increase Athletic Performance

EROS having Tongkat Ali enhances your testosterone level thus it can help in the significant loss of body fat along with boosting the body to gain lean body stature. In addition to that more significant improvement can be seen if exercise along with EROS is taken on a daily routine basis.

A research study published in Malaysia in 2002 depicted that Tongkat Ali had the ability to enhance lean body mass significantly. In this research study, a group of 7 men was given Tongkat Ali at the dose rate of 100 mg per person in a single day for a time period of 5 weeks. These men experienced an increase in 5% in their lean body muscles and a prominent decline in body fat.

 

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Maca

History

According to history, ancient warriors took maca as a booster before the beginning of the battle to make them physically powerful. But later on they prohibited themselves from taking Maca, in order to restrain themselves to conquer females from their increased sex libidos. Maca which is chief and integral part of our product is a way of life. Actually it is similar a root vegetable like a turnip or reddish and excessively used in cakes, soups, drinks, bread in countries like Peru. Maca is grown at altitudes in the mountains of Andes nearly 14,000 ft in very fertile soils. This root vegetable is very effective in extracting minerals of important human health from the fertile soil, thus forming its mineral concentration very high. The Latin name of this MACA is called “Lepidium meyenii” and other common names of this vegetable include Maino, Maca-Maca, Ayak Willku, and Ayak Chichira. The origin of this Maca is the continent of South America. Chief parts of this vegetable which is in use for eating as well as for medicinal purpose is root.

Health Benefits and traditional use of Maca

Native to the Andes mountain range, Maca has long been used by the indigenous peoples of this region to promote sexual function and fertility. The Incans used Maca in many of their natural remedies, specifically to enhance energy, increase stamina, endurance and strength. It is also known as Peruvian Ginseng due to its stimulating qualities.

 

Maca Benefits

Endocrine Health

Maca is also called as  “food for endocrine glands”. The endocrine system consists of various glands that secrete hormones capable of regulating and maintaining metabolism, development and growth, sexual function, tissue function, sleep, reproduction, mood and response to anxiety, stress, and injury. Our product EROS having optimum quantity of maca extract which supports your endocrine system having glands do its job properly, particularly during sub-optimal situations, like when you are anxious or stressed. The key role of this ingredient present in EROS stimulates the endocrine system which stimulates your pituitary gland. When pituitary gland is performing at its best, the whole endocrine system work in balanced condition.

Enhance Sexual Health

Our product Eros main constituent Maca plays a key role by primarily balancing the hormonal system. This strong root helps to boost up the male libido potency. A powerful fertility booster, research studies indicated that in men it helps to enhance sperm volume, motility, and quality.

Reduce Anxiety and Stress

In your fast-paced daily hectic routines, stress and anxiety can be not be avoided. One of the signs of stress may be “adrenal fatigue”. Eros having Maca can help this issue is by restraining its adaptogenic features to regulate and maintain the hormones secreted by this gland.

Boost your Energy and Mood

Due to optimum adaptogenic qualities and nutritional content, our product EROS a male enhancer’s main ingredient Maca will ultimately have a better effect on level of energy, mood, and stamina. As powerhouse of nutrition, Maca is filled naturally with vitamins, protein, minerals, and other phytonutrients especially particularly B Vitamins which are famous for their quality of boosting brain and cognitive abilities.

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Pumpkin

 Although the pumpkin is scientifically viewed as a fruit (due to the presence of seeds) it is often consumed as a vegetable in Indian households, because of the properties that make it similar to a vegetable.

It improves your vision

Pumpkin is extremely rich in Vitamin A. One cup of cubed pumpkin contains almost twice the Vitamin A required by our body on a daily basis. Vitamin A promotes eye health. It also helps in maintaining healthy skin, bone, and teeth.

It gives your immunity a boost.

Densely packed with essential nutrients, pumpkin can give your immunity the much-required boost. People with Vitamin A deficiency can have a weaker immune system. It is rich in Vitamin A and Vitamin C that can boost the immune system and increase the production of white cells respectively. Vitamin E, iron and folate are also present in pumpkin.

It reduces the risk of chronic diseases.

The free radicals produced by our body’s metabolic processes can create a state of oxidative stress, which can be linked to chronic illnesses, including cancer and heart disease. Pumpkin contains antioxidants—alpha-carotene, beta-carotene, and beta-cryptoxanthin. These antioxidants can neutralize the free radicals and prevent your cells from getting damaged. Also, the antioxidants present in pumpkin have proven to protect skin against sun damage and lower the risk of cancer and eye diseases.

It helps promote weight loss.

Despite being densely packed with nutrients, pumpkin is incredibly low in calories. 250 grams of pumpkin has only 50 calories and is 94 per cent of water. You can have more of it and still not exceed your daily calorie intake required to lose weight. Pumpkin is also a decent source of fiber, which keeps you fuller for longer.

It helps maintain healthy skin.

The carotenoids in pumpkin are great for your skin. These carotenoids are turned into Vitamin A by your body. Studies show carotenoids like beta-carotene can act as a natural sunblock. Vitamin C present in pumpkin also makes your skin better.

It can be used across various dishes.

Pumpkin is delicious and easy to incorporate in your diet. It can be added to pies, custard, pancake, roasted veggies, pasta, dal, and soups.

Its seeds offer several health benefits.

Even the seeds of the pumpkin are packed with nutrients and offer many health benefits. Pumpkin seeds are said to improve bladder, heart health and promote weight loss.

It’s loaded with essential minerals, such as iron, potassium, and magnesium.

One small serving of pumpkin contains 250 milligrams of potassium and the same small serving of pumpkin also contains a good amount of iron. One cup has a little less than 10 per cent of your recommended daily allowance of iron.

Our body needs magnesium for maintaining normal muscle function and for boosting our immune systems, among other things. Pumpkin seeds provide us with enough magnesium to perform these functions well.

It boosts sex life.

Pumpkin seeds are rich in zinc, which plays an important role in men’s sexual health, including their fertility, sex drive, and potency, claims Discovery Fit and Health.

 

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L-Arginine

 

Fertility issues:  Arginine is a semi-essential amino acid usually taken as a dietary supplement by males facing fertility issues. L-arginine is an amino acid utilized in a number of body metabolic functions. The body is capable to form L-­arginine, but dietary supplement intake is essential for providing enough concentration of this amino acid. L-arginine is chief value which is an important part of our product required for optimum health and is able to defend body against multiple health issues or pathological conditions.

Supports and help healthy libido: As L-arginine has the ability to increase blood flow it may also lead to an increased libido.This supplement may increase sexual arousal, support sexual performance, and satisfaction. Our l-arginine supplement will make sexual stimulation more sensitive and increases libido and desire for sex.

Effects on belly fat: Although arginine is known for its muscle-building capabilities, it can also help to deal with obesity by helping to reduce fat, including belly fat. In order to cut the fat, our natural arginine supplements can play a role in helping to burn fat from belly and waist.

Arginine for weight loss: Taking arginine supplements may be helpful in burning more fat. Arginine supplements may also increase the levels of nitric oxide, which helps to quickly burn fat within the body. Nitric oxide helps to relax blood vessels and helps them to open up. When the vessels open up, this helps to increase blood flow and the delivery of oxygen, as well as nutrients, throughout the body, including to muscles

 

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Suggested use

As a dietary supplement take two tablets once a day. For best results take 20 to 30 minutes before a meal with 80Z water or as directed by your health care professional.

Caution

This product is not intended for pregnant or lactating women, adolescents, individuals on restricted diet, person with high blood pressure or heart problem. If you have known medical condition you should consult with a medical professional before using this or any dietary supplement.

Keep out of reach of children, do not use itself if safety seal is damaged or missing. Store in a dry and cold place.   

 

References:

  1. Khosronezhad N, Hosseinzadeh Colagar A, Mortazavi SM. The Nsun7 (A11337)-deletion mutation, causes reduction of its protein rate and associated with sperm motility defect in infertile men. J Assist Reprod Genet. 2015;32(5):807–15. [PMC free article] [PubMed] [Google Scholar]
  2. Yuyan L, Junqing W, Wei Y, Weijin Z, Ersheng G. Are serum zinc and copper levels related to semen quality? Fertil Steril. 2008;89(4):1008–11. [PubMed] [Google Scholar]
  3. Khan MS, Zaman S, Sajjad M, Shoaib M, Gilani G. Assessment of the level of trace element zinc in seminal plasma of males and evaluation of its role in male infertility. Int J Appl Basic Med Res. 2011;1 (2):93–6. [PMC free article] [PubMed] [Google Scholar]
  4. Yan M, Hardin K, Ho E. Differential response to zinc-induced apoptosis in benign prostate hyperplasia and prostate cancer cells. J Nutr Biochem. 2010; 21(8):687–94. [PMC free article] [PubMed] [Google Scholar]
  5. Yamaguchi S, Miura C, Kikuchi K, Celino FT, Agusa T, Tanabe S, et al. Zinc is an essential trace element for spermatogenesis. Proc Natl Acad Sci USA. 2009;106(26):10859–64. [PMC free article] [PubMed] [Google Scholar]
  6. Colagar AH, Marzony ET, Chaichi MJ. Zinc levels in seminal plasma are associated with sperm quality in fertile and infertile men. Nutr Res. 2009;29(2):82–8. [PubMed] [Google Scholar]
  7. Swain PS, Rao SB, Rajendran D, Dominic G, Selvaraju S. Nano zinc, an alternative to conventional zinc as animal feed supplement: A review. Anim Nutr. 2016;2(3):134–41. [PMC free article] [PubMed] [Google Scholar]
  8. Prasad AS. Discovery of human zinc deficiency: its impact on human health and disease. Advances in Nutrition. Adv Nutr. 2013;4(2):176–90. [PMC free article] [PubMed] [Google Scholar]
  9. Zhao CY, Tan SX, Xiao XY, Qiu XS, Pan JQ, Tang ZX. Effects of dietary zinc oxide nanoparticles on growth performance and antioxidative status in broilers. Biol Trace Elem Res. 2014;160(3):361–7. [PubMed] [Google Scholar]
  10. Parashuramulu S, Nagalakshmi D, Rao DS, Kumar MK, Swain P. Effect of Zinc supplementation on antioxidant status and immune response in buffalo calves. Anim Nutr Feed Technol. 2015;15(2):179–88. [Google Scholar]
  11. Chia SE, Ong CN, Chua LH, Ho LM, Tay SK. Comparison of zinc concentrations in blood and seminal plasma and the various sperm parameters between fertile and infertile men. J Androl. 2000; 21(1):53–7. [PubMed] [Google Scholar]
  12. Eggert-Kruse W, Zwick EM, Batschulat K, Rohr G, Armbruster FP, Petzoldt D, et al. Are zinc levels in seminal plasma associated with seminal leukocytes and other determinants of semen quality? Fertil Steril. 2002;77(2):260–9. [PubMed] [Google Scholar]
  13. García-Contreras A, De Loera Y, García-Artiga C, Palomo A, Guevara JA, Herrera-Haro J, et al. Elevated dietary intake of Zn-methionate is associated with increased sperm DNA fragmentation in the boar. Reprod Toxicol. 2011;31(4):570–3. [PubMed] [Google Scholar]
  14. Plum LM, Rink L, Haase H. The essential toxin: impact of zinc on human health. Int J Environ Res Public Health. 2010;7(4):1342–65. [PMC free article] [PubMed] [Google Scholar]
  15. Sauer AK, Hagmeyer S, Grabrucker AM. Zinc Deficiency. In: Erkekoglu P, Kocel-Gumusel B, editors. , editors Nutritional deficiency. Rijeka: InTech Open Science; 2016: p. 23–46. [Google Scholar]
  16. Wani AL, Parveen N, Ansari MO, Ahmad MF, Jameel S, Shadab G. Zinc: An element of extensive medical importance. Curr Med Res Pract. 2017;7 (3):90–8. [Google Scholar]
  17. Wong WY, Flik G, Groenen PM, Swinkels DW, Thomas CM, Copius-Peereboom JH, et al. The impact of calcium, magnesium, zinc, and copper in blood and seminal plasma on semen parameters in men. Reprod Toxicol. 2001;15(2):131–6. [PubMed] [Google Scholar]
  18. Hambidge M. Human zinc deficiency. J Nutr. 2000; 130(5):1344S–49S. [PubMed] [Google Scholar]
  19. Frederickson CJ, Koh JY, Bush AI. The neurobiology of zinc in health and disease. Nat Rev Neurosci. 2005;6(6):449–62. [PubMed] [Google Scholar]
  20. Rink L, Gabriel P. Zinc and the immune system. Proc Nutr Soc. 2000;59(4):541–52. [PubMed] [Google Scholar]
  21. Haase H, Rink L. The immune system and the impact of zinc during aging. Immun Ageing. 2009; 6:9. [PMC free article] [PubMed] [Google Scholar]
  22. Boran C, Ozkan KU. The effect of zinc therapy on damaged testis in pre-pubertal rats. Pediatr Surg Int. 2004;20(6):444–8. [PubMed] [Google Scholar]
  23. Elgazar V, Razanov V, Stoltenberg M, Hershfinkel M, Huleihel M, Nitzan YB, et al. Zinc-regulating proteins, ZnT-1, and metallothionein I/II are present in different cell populations in the mouse testis. J Histochem Cytochem. 2005;53(7):905–12. [PubMed] [Google Scholar]
  24. Hunt CD, Johnson PE, Herbel J, Mullen LK. Effects of dietary zinc depletion on seminal volume and zinc loss, serum testosterone concentrations, and sperm morphology in young men. Am J Clin Nutr. 1992;56(1):148–57. [PubMed] [Google Scholar]
  25. Ali H, Ahmed M, Baig M, Ali M. Relationship of zinc concentrations in blood and seminal plasma with various semen parameters in infertile subjects. Pak J Med Sci. 2007;23(1):111–4. [Google Scholar]
  26. Croxford TP, McCormick NH, Kelleher SL. Moderate zinc deficiency reduces testicular Zip6 and Zip10 abundance and impairs spermatogenesis in mice. J Nutr. 2011;141(3):359–65. [PMC free article] [PubMed] [Google Scholar]
  27. Deng CH, Zheng B, She SF. [A clinical study of biological zinc for the treatment of male infertility with chronic prostatitis]. Zhonghua Nan Ke Xue. 2005;11(2):127–9. Chinese. [PubMed] [Google Scholar]
  28. Albert A. Selective toxicity: the physico-chemical basis of therapy. 6th ed Netherlands: Springer; 2012. 368 p. [Google Scholar]
  29. Vijayalakshmi K, Sivaraj D. Enhanced antibacterial activity of Cr doped ZnO nanorods synthesized using microwave processing. RSC Adv. 2015;5 (84):68461–9. [Google Scholar]
  30. Cheah Y, Yang W. Functions of essential nutrition for high quality spermatogenesis. Adv Biosci Biotechnol. 2011;2(4):182. [Google Scholar]
  31. Foresta C, Garolla A, Cosci I, Menegazzo M, Ferigo M, Gandin V, et al. Role of zinc trafficking in male fertility: from germ to sperm. Hum Reprod. 2014;29(6):1134–45. [PubMed] [Google Scholar]
  32. Roy B, Baghel RPS, Mohanty TK, Mondal G. Zinc and male reproduction in domestic animals: A review. Indian J Anim Nutr. 2013;30(4):339–50. [Google Scholar]
  33. Oliva A, Dotta A, Multigner L. Pentoxifylline and antioxidants improve sperm quality in male patients with varicocele. Fertil Steril. 2009;91(4 Suppl):1536–9. [PubMed] [Google Scholar]
  34. Merrells KJ, Blewett H, Jamieson JA, Taylor CG, Suh M. Relationship between abnormal sperm morphology induced by dietary zinc deficiency and lipid composition in testes of growing rats. Br J Nutr. 2009;102(2):226–32. [PubMed] [Google Scholar]
  35. Fathi E, Farhzadi R. Survey on impact of trace elements (Cu, Se AND Zn) on veterinary and human mesenchymal stem cells. Rom J Biochem. 2015;52 (1):67–77. [Google Scholar]
  36. Ghasemzadeh-Hasankolai M, Batavani R, Eslaminejad MB, Sedighi-Gilani M. Effect of zinc ions on differentiation of bone marrow-derived mesenchymal stem cells to male germ cells and some germ cell-specific gene expression in rams. Biol Trace Elem Res. 2012;150(1–3):137–46. [PubMed] [Google Scholar]
  37. Omu A, Al-Azemi MK, Kehinde EO, Anim JT, Oriowo MA, Mathew TC. Indications of the mechanisms involved in improved sperm parameters by zinc therapy. Med Princ Pract. 2008;17(2):108–16. [PubMed] [Google Scholar]
  38. Kendall NR, McMullen S, Green A, Rodway RG. The effect of a zinc, cobalt and selenium soluble glass bolus on trace element status and semen quality of ram lambs. Anim Reprod Sci. 2000;62 (4):277–83. [PubMed] [Google Scholar]
  39. Akinloye O, Abbiyesuku FM, Oguntibeju OO, Arowojolu AO, Truter EJ. The impact of blood and seminal plasma zinc and copper concentrations on spermogram and hormonal changes in infertile Nigerian men. Reprod Biol. 2011;11(2):83–98. [PubMed] [Google Scholar]
  40. Dissanayake D, Wijesinghe P, Ratnasooriya W, Wimalasena S. Relationship between seminal plasma zinc and semen quality in a subfertile population. J Hum Reprod Sci. 2010;3(3):124–8. [PMC free article] [PubMed] [Google Scholar]
  41. Carpino A, Siciliano L, Petroni M, De Stefano C, Aquila S, Ando S, et al. Low seminal zinc bound to high molecular weight proteins in asthenozoospermic patients: evidence of increased sperm zinc content in oligoasthenozoospermic patients. Hum Reprod. 1998;13(1):111–4. [PubMed] [Google Scholar]
  42. Mankad M, Sathawara N, Doshi H, Saiyed H, Kumar S. Seminal plasma zinc concentration and α-glucosidase activity with respect to semen quality. Biol Trace Elem Res. 2006;110(2):97–106. [PubMed] [Google Scholar]
  43. Danscher G, Hammen R, Fjerdingstad E, Rebbe H. Zinc content of human ejaculate and the motility of sperm cells. Int J Androl. 1978;1(1–6):576–81. [Google Scholar]
  44. Zhao R, Xiong CL. [Zinc content analysis in serum, seminal plasma and spermatozoa of asthenozoospermic and oligoasthenozoospermic patients]. Zhonghua Nan Ke Xue. 2005;11(9):680–2. Chinese. [PubMed] [Google Scholar]
  45. Lin YC, Chang TC, Tseng YJ, Lin YL, Huang FJ, Kung FT, et al. Seminal plasma zinc levels and sperm motion characteristics in infertile samples. Chang Gung Med J. 2000;23(5):260–6. [PubMed] [Google Scholar]
  46. Henkel R, Bittner J, Weber R, Hüther F, Miska W. Relevance of zinc in human sperm flagella and its relation to motility. Fertil Steril. 1999;71(6):1138–43. [PubMed] [Google Scholar]
  47. Muhammadamin K, Darweesh OO, Alshawni MA. Evaluation of testosterone hormone and zinc levels among infertile males in Kirkuk province/Iraq. Zanco J Med Sci. 2011;15(2):34–9. [Google Scholar]
  48. Hussain NK, Rzoqi SS, Numan AW, Ali DT. A comparative study of fructose, zinc and copper levels in seminal plasma in fertile and infertile men. Iraqi J Med Sci. 2000;48.
  49. Liu DY, Sie BS, Liu ML, Agresta F, Baker HW. Relationship between seminal plasma zinc concentration and spermatozoa–zona pellucida binding and the ZP-induced acrosome reaction in subfertile men. Asian J Androl. 2009;11(4):499–507. [PMC free article] [PubMed] [Google Scholar]
  50. Badade ZG, More K, Narshetty J. Oxidative stress adversely affects spermatogenesis in male infertility. Biomed Res. 2011;22(3):319–22. [Google Scholar]
  51. Guo CH, Chen PC, Yeh MS, Hsiung DY, Wang CL. Cu/Zn ratios are associated with nutritional status, oxidative stress, inflammation, and immune abnormalities in patients on peritoneal dialysis. Clin Biochem. 2011;44(4):275–80. [PubMed] [Google Scholar]
  52. Jawad HM. Zinc sulfate treatment of secondary male infertility associated with positive serum and seminal plasma anti-sperm antibody test. Middle East Fertil Soc J. 2013;18(1):24–30. [Google Scholar]
  53. Jurkowski TP, Ravichandran M, Stepper P. Synthetic epigenetics-towards intelligent control of epigenetic states and cell identity. Clin Epigenetics. 2015;7:18. [PMC free article] [PubMed] [Google Scholar]
  54. Wessels I. Epigenetics and metal deficiencies. Curr Nutr Rep. 2014;3(3):196–203. [Google Scholar]
  55. Kessels JE, Wessels I, Haase H, Rink L, Uciechowski P. Influence of DNA-methylation on zinc homeostasis in myeloid cells: Regulation of zinc transporters and zinc binding proteins. J Trace Elem Med Biol. 2016;37:125–33. [PubMed] [Google Scholar]
  56. Ebisch IM, Thomas CM, Peters WH, Braat DD, Steegers-Theunissen RP. The importance of folate, zinc and antioxidants in the pathogenesis and prevention of subfertility. Hum Reprod Update. 2007; 13(2):163–74. [PubMed] [Google Scholar]
  57. Josarayi GA, Mohammad-Hasani A, Aftabi Y, Moudi E, Hosseinzadeh Colagar A. The AhRR-c. 565C> G transversion may increase total antioxidant capacity levels of the seminal plasma in infertile men. Environ Sci Pollut Res Int. 2017;24 (21):17428–35. [PubMed] [Google Scholar]
  58. Jahantigh D, Hosseinzadeh Colagar A, Salimi S. Genetic polymorphisms and haplotypes of the DJ-1 gene promoter associated with the susceptibility to male infertility. J Assist Reprod Genet. 2017;34 (12):1673–82. [PMC free article] [PubMed] [Google Scholar]
  59. Powell SR. The antioxidant properties of zinc. J Nutr. 2000;130(5S Suppl):1447S–54S. [PubMed] [Google Scholar]
  60. Saleh RA, Agarwal A, Sharma RK, Nelson DR, Thomas AJ., Jr Effect of cigarette smoking on levels of seminal oxidative stress in infertile men: a prospective study. Fertil Steril. 2002;78(3):491–9. [PubMed] [Google Scholar]
  61. Kumosani T, Elshal M, Al-Jonaid A, Abduljabar HS. The influence of smoking on semen quality, seminal microelements and Ca 2+-ATPase activity among infertile and fertile men. Clin Biochem. 2008;41(14–15):1199–203. [PubMed] [Google Scholar]
  62. Liu RZ, Gao JC, Zhang HG, Wang RX, Zhang ZH, Liu XY. Seminal plasma zinc level may be associated with the effect of cigarette smoking on sperm parameters. J Int Med Res. 2010;38(3):923–8. [PubMed] [Google Scholar]
  63. Kiziler AR, Aydemir B, Onaran I, Alici B, Ozkara H, Gulyasar T, et al. High levels of cadmium and lead in seminal fluid and blood of smoking men are associated with high oxidative stress and damage in infertile subjects. Biol Trace Elem Res. 2007; 120(1–3):82–91. [PubMed] [Google Scholar]
  64. Chari MG, Hosseinzadeh Colagar A. Seminal plasma lipid peroxidation, total antioxidant capacity, and cigarette smoking in asthenoteratospermic men. J Mens Health. 2011;8(1):43–9. [Google Scholar]
  65. Meletis CD, Barker J. Natural ways to enhance male fertility. Altern Complement Ther. 2004;10 (1):22–7. [Google Scholar]
  66. Sensi SL, Paoletti P, Bush AI, Sekler I. Zinc in the physiology and pathology of the CNS. Nat Rev Neurosci. 2009;10(11):780–91. [PubMed] [Google Scholar]
  67. Kambe T, Tsuji T, Hashimoto A, Itsumura N. The physiological, biochemical, and molecular roles of zinc transporters in zinc homeostasis and metabolism. Physiol Rev. 2015;95(3):749–84. [PubMed] [Google Scholar]
  68. Schneider M, Förster H, Boersma A, Seiler A, Wehnes H, Sinowatz F, et al. Mitochondrial glutathione peroxidase 4 disruption causes male infertility. FASEB J. 2009;23(9):3233–42. [PubMed] [Google Scholar]
  69. Mogielnicka-Brzozowska M, Kordan W. Characteristics of selected seminal plasma proteins and their application in the improvement of the reproductive processes in mammals. Pol J Vet Sci. 2011; 14(3):489–99. [PubMed] [Google Scholar]
  70. Khosronezhad N, Colagar AH, Jorsarayi SG. C26232T mutation in Nsun7 gene and reduce sperm motility in asthenoteratospermic men. J Genet Resour. 2015;1(1):25–30. [Google Scholar]
  71. Eide DJ. Zinc transporters and the cellular trafficking of zinc. Biochim Biophys Acta. 2006;1763(7): 711–22. [PubMed] [Google Scholar]
  72. Himeno S, Yanagiya T, Fujishiro H. The role of zinc transporters in cadmium and manganese transport in mammalian cells. Biochimie. 2009;91(10): 1218–22. [PubMed] [Google Scholar]
  73. Song Y, Elias V, Loban A, Scrimgeour AG, Ho E. Marginal zinc deficiency increases oxidative DNA damage in the prostate after chronic exercise. Free Radic Biol Med. 2010;48(1):82–8. [PMC free article] [PubMed] [Google Scholar]
  74. Tamano H, Koike Y, Nakada H, Shakushi Y, Takeda A. Significance of synaptic Zn2+ signaling in zincergic and non-zincergic synapses in the hippocampus in cognition. J Trace Elem Med Biol. 2016;38:93–8. [PubMed] [Google Scholar]
  75. Gopalsamy GL, Alpers DH, Binder HJ, Tran CD, Ramakrishna BS, Brown I, et al. The relevance of the colon to zinc nutrition. Nutrients. 2015;7(1): 572–83. [PMC free article] [PubMed] [Google Scholar]
  76. Hu Y, Liu Y, Kim G, Jun EJ, Swamy K, Kim Y, et al. Pyrene based fluorescent probes for detecting endogenous zinc ions in live cells. Dyes Pigm. 2015;113:372–7. [Google Scholar]
  77. Antignani A, Youle RJ. How do Bax and Bak lead to permeabilization of the outer mitochondrial membrane? Curr Opin Cell Biol. 2006;18(6):685–9. [PubMed] [Google Scholar]
  78. Park SE, Park JW, Cho YS, Ryu JH, Paick JS, Chun YS. HIF-1alpha promotes survival of prostate cells at a high zinc environment. Prostate. 2007;67(14):1514–23. [PubMed] [Google Scholar]
  79. Bae SN, Kim J, Lee YS, Kim JD, Kim MY, Park LO. Cytotoxic effect of zinc–citrate compound on choriocarcinoma cell lines. Placenta. 2007;28(1): 22–30. [PubMed] [Google Scholar]
  80. Zhao J, Dong X, Hu X, Long Z, Wang L, Liu Q, et al. Zinc levels in seminal plasma and their correlation with male infertility: A systematic review and meta-analysis. Sci Rep. 2016;6:22386. [PMC free article] [PubMed] [Google Scholar]
  81. Feng P, Li T, Guan Z, Franklin RB, Costello LC. The involvement of Bax in zinc-induced mitochondrial apoptogenesis in malignant prostate cells. Mol Cancer. 2008;7:25. [PMC free article] [PubMed] [Google Scholar]
  82. Miyai T, Hojyo S, Ikawa T, Kawamura M, Irié T, Ogura H, et al. Zinc transporter SLC39A10/ZIP10 facilitates antiapoptotic signaling during early B-cell development. Proc Natl Acad Sci USA. 2014; 111(32):11780–5. [PMC free article] [PubMed] [Google Scholar]